The utility model discloses a waterproof and moisture resistant industrial power cable which comprises a cable body which comprises conductors, a shielding layer, an insulating layer and an outer sheath. The cross section of the cable body is a round structure. The cable body is internally provided with a plurality of conductors. A rubber frame is arranged among the conductors to separate the conductors. The outer side of the rubber frame is provided with the insulating layer. The gap between the insulating layer and the rubber frame is provided with a filler. The shielding layer is extruded outside the insulating layer. A water blocking belt, a metal sheath and the outer sheath are orderly extruded outside the shielding layer from inside to outside. The water blocking belt is internally provided with a plurality of drainage cores. A hot melt adhesive layer is arranged between the metal sheath and the outer sheath. The waterproof and moisture resistant industrial power cable has the advantages of reasonable structure design, good waterproof performance and long service life.